Epidemiological analysis off MP pneumonia and you can RWE out-of 2003 so you’re able to 2014

Analytical study

All calculations were performed with SPSS V.14.0 (SPSS Inc.)parisons between groups were performed using the Student’s t-test, ? 2 test and Fisher’s exact test, and the data were expressed as mean±SD for continuous variables. A p value of <0.05 was considered statistically significant.

Efficiency

The fresh subjects in the modern analysis was basically 793 people having MP pneumonia and you will 384 patients which have RWE into the research months. Getting epidemiological evaluation, a whole 793 people were utilized, once the found during the in earlier times penned post.fourteen To have health-related assessment amongst the communities, a total of 501 MP pneumonia clients that were admitted during the the previous epidemics (241 cases when you look at the 2007–2006, and you may 260 cases last year), and you will 384 customers which have RWE had been analysed (contour 1). Inside analysis several months, the entire amount of acknowledge clients from the our very own institution are good overall 25 911 (but garden center people). There were whenever 2100 admitted customers annually with a few distinctions in each year.

Much of MP pneumonia customers had realize-right up period at the least three years out of past epidemic seasons off 2011, nevertheless follow-right up subjects pleased with our very own possibilities criteria was 180 certainly 501 times regarding the MP pneumonia class and you can 206 among 384 circumstances about RWE category.

In MP pneumonia clients, there are clear episodes out-of circumstances into the 2003, 2006–2007 and you can 2011, with a few instances happening on interepidemic symptoms. There are apparently steady quantities of RWE instances each year throughout the study several months. There have been zero associated improved times in MP pneumonia epidemic decades except within the 2007 (contour 2). No jak dziaÅ‚a colombian cupid MP pneumonia patient who had been readmitted due to MP reinfection along side epidemics was observed throughout data period. The new mean ages and age shipments was indeed equivalent, and peak age groups were dos–five years old in teams (shape step three). Into the seasonality out-of each other communities, MP pneumonia was commonplace inside decreasing acquisition away from autumn, june, wintertime and you will springtime, whenever you are customers which have RWE have been most common in autumn, with springtime, winter and summer (research perhaps not shown).

Market and you may medical functions out of MP pneumonia and you can RWE groups

Demographic, clinical and laboratory data in both groups are shown in table 1. The mean age and age distribution were similar in both groups as shown in figure 3 (5.4 years vs 5.6 years, p=0.312). Both groups had male predominance, and there were more males in the RWE group. As expected, cases with wheezing at presentation, the proportion of patients with history or family history of allergic diseases, and history of wheezing were higher in the RWE group. Recurrent wheezing after discharge was observed in 38 of 180 patients with MP pneumonia and 141 of the 206 patients with RWE (p<0.001).

In MP pneumonia patients, 52 of the total 501 patients (10.4%) had wheezing at presentation, 72 (14.4%) had a history of allergic diseases, 15 (3%) had RWE according to our definition and 40 (8%) had a family history of allergic diseases. When we divided the MP pneumonia patients into two groups of patients with wheezing (n=52) and without wheezing (n=449), the patients with wheezing were younger (3.7 years vs 5.6 years, p<0.001) and had higher proportions of history allergic diseases and wheezing history and higher values of leucocyte count and eosinophil differential (table 2). Among the 52 MP pneumonia patients with wheezing at admission, 10 were patient with RWE, while 42 had no previous RWE history. Thus, in this study, 66% (10 of 15) of patients with RWE history presented with wheezing, while 8.6% of patients without RWE history (42 of 486) had wheezing at presentation. In a follow-up study of patients who visited two or more times after discharge, 13 (including 5 cases of RWE) of 21 MP pneumonia patients with initial wheezing and 25 (including 2 cases of RWE) of 159 MP pneumonia patients without wheezing had at least one wheezing episode after discharge (table 2). Although not all patients were followed-up, it was estimated that at least 31 of the total MP pneumonia patients (n=501, 6.2%) showed a recurrent wheezing after initial MP infection.